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They were asked to refrain from using LABA after this point, unless they had a severe exacerbation (an event requiring treatment with oral corticosteroids, as judged by the investigator, or a decrease in the morning PEF, for 1 or more days, of more than 30% below the average baseline morning PEF recorded during the week immediately preceding withdrawal from LABA therapy), or if they were judged by the investigator to have poor asthma control that required the resumption of LABA.

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Allen and colleagues conducted a double-blind, placebo-controlled study with 325 pediatric asthma patients, age range of 4 to 11 years old, who were randomly assigned to receive a low dose of fluticasone (50 µg), a higher dose of fluticasone (100 µg), or a placebo twice daily for 1 year.

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Serevent Inhaler contains a bronchodilator medicine referred to as a long-acting beta-adrenoceptor agonist (LABA) that is prescribed for those dealing with asthma or chronic obstructive pulmonary disease (COPD).

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Clean fluticasone inhaler at least once a week after the evening dose by removing the mouthpiece cap from the inhaler and washing the mouthpiece with moistened cotton; allow the actuator to air-dry overnight.

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Educating parents and caregivers of children with asthma to recognize and avoid triggers, and to understand the use of prescribed medications, the proper use of inhalation devices, and the importance of compliance and monitoring, has been shown to improve lung function and decrease school absenteeism and visits to the emergency department.

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SEEK MEDICAL ATTENTION RIGHT AWAY if any of these SEVERE side effects occur: chest pain; choking; fast or irregular heartbeat; fever; new or worsening asthma or COPD symptoms (eg, coughing, increased chest tightness, shortness of breath, wheezing); overexcitement; severe or persistent headache or dizziness; severe or persistent muscle pain or cramps; symptoms of high blood sugar (eg, increased thirst, urination, or hunger; unusual weakness or drowsiness; confusion).

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The typical COPD patient is a current or former smoker, over age 50, with a pack-a-day habit of more than 20 years.

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Glaxo declined to participate because Spiriva is not approved for treating asthma.

Treatment of chronic asthma therefore involves regular use of anti-inflammatory drugs (preventer) to stabilize the disease along with the use of bronchodilator drugs (relievers) to provide relief from symptoms as and when these occur.

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Adherence to long-term therapy is an important consideration in the treatment of any chronic disease, and asthma is no exception.

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An inhaler is a device holding a medicine that you take by breathing in (inhaling).

These agents do not significantly improve lung function, symptoms, or overall outcomes when used for acute exacerbations.

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Evidence suggests that life-threatening asthma attacks may be less likely to occur when these agents are used in conjunction with an inhaled steroid.

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