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Selegiline is a revolutionary medication for me because during my long years of 'collaboration' with depression it was the only medication that managed to improve my condition without causing serious side effects like drowsiness or vomiting. I take it on a regular basis two times per year and with this drug I can feel myself to be an absolutely normal person. Quite a new sensation for me.)

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After maximum clinical response is achieved, an attempt should be made to reduce the dosage slowly over a period of several weeks without jeopardizing the therapeutic response.

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Monoamine oxidase inhibitors (MAOIs) work by inhibiting the enzyme monoamine oxidase.

The FDA has approved EMSAM (selegiline transdermal system), a monoamine oxidase inhibitor (MAOI) and the first transdermal therapy for the treatment of major depressive disorder in adults.

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The PDR is a legal, not a medical, document, so I don't think their doses are always reliable.

With overdosage, in order to avoid the occurrence of hypertensive crisis ("cheese reaction"), dietary tyramine should be restricted for several weeks beyond recovery to permit regeneration of the peripheral MAO-A isoenzyme.

If you suddenly stop taking medications for Parkinson's disease such as selegiline, you may experience fever, sweating, stiff muscles, and loss of consciousness.

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Emsam is an antidepressant of the monoamine oxidase (MAO) inhibitor class and is used for the treatment of depression.

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The clinical relevance to EMSAM (selegiline transdermal system) is unknown.

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Some anticonvulsant medications, such as divalproex (Depakote) and gabapentin (Neurontin), may have a role in the treatment of anxiety disorders, especially in patients with high potential for abusing benzodiazepines.

The use of MAOIs should be limited to cases in which SSRIs are ineffective or cannot be afforded.

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Patients who have these symptoms should get medical care right away.

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It contains important information about certain changes in diet that might be needed, other medications to avoid, and other important information about this medication.

Healing is a process that takes time and it is important not to give up.

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Results can be seen very quickly, in as little as one treatment, but are often not seen until after the full course of treatment is complete.

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Recently, Dye and now Mylan Pharmaceutical took over the marketing of EMSAM from Bristol-Myers Squibb.

Serotonin Syndrome: The development of a potentially life-threatening serotonin syndrome has been reported with concomitant use of MAOIs, such as EMSAM, with serotonergic drugs.

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Call the healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.

Tell your doctor if you are pregnant or plan to become pregnant while using Zomig.

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If you discover that you have missed a dose the same day you were supposed to take it, you may take the dose immediately; however, if you remember the day after you missed the dose, do not take a double dose to compensate.

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Anorexia was reported as a very common side effect with selegiline (the active ingredient contained in Emsam) in double-blind placebo-controlled clinical trials when used as adjunctive therapy with levodopa in the earlier phases of Parkinson's disease.

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Do not drive or operate dangerous machinery until you know how Emsam affects you.

Due to the many dietary restrictions and potentially dangerous drug interactions associated with MAOIs, SSRIs and TCAs are often preferred.

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Monoamine oxidase inhibitors (MAOIs) were the first type of antidepressant developed.

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Quetiapine has a pending application for approval by the FDA for use in generalized anxiety disorder as well as in major depressive disorder for patients whose symptoms do not remit with other treatments as it seems that low doses (50-300 mg range) of quetiapine may not be associated with the risk of hyperglycemia and metabolic syndrome that potentially can occur in higher dosage ranges or with other antipsychotic medications.

Oral selegiline is an effective AD, but not as effective as EMSAM (as I understand it), because you'd have to take so much more to get the same effective levels in your blood.

It will most likely be marketed for everything from stress urinary incontinence, social phobia and generalised anxiety disorder, diabetic peripheral neuropathic pain and possibly irritable bowel syndrome.

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Do not use the medication in larger amounts or for longer than recommended.

Serious, sometimes fatal, central nervous system (CNS) toxicity referred to as the "serotonin syndrome" has been reported with the combination of non-selective MAOIs with certain other drugs, including tricyclic or selective serotonin reuptake inhibitor antidepressants, amphetamines, meperidine, or pentazocine.

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