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Imiquimod Cream, 5% Important: For use on the skin only (topical).
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Therapies such as interferon (IFN) and imiquimod treat the infection by stimulating immune responses (); the catechins has been involved in the regression of genital warts through the cell cycle arrest, apoptosis induction and the inhibition of HPV gene expression ().
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Similar to the pretreatment education process used for patients treated with 5-FU, we educate patients that signs of inflammation, including itching, burning, and pain, are evidence that the imiquimod treatment is working, and are expected if treatment is successful.
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In Example 23 herein above, formulations 126 and 182, wherein the fatty acid isa, are the formulations that are used in Examples 24-28 and in FIGS.
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Garra A (2010) The regulation of IL-10 production by immune cells.
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Advise patients being treated for genital HPV warts to avoid sexual (genital, anal, oral) contact while imiquimod cream is on the skin and that the cream may weaken condoms and vaginal diaphragms.
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It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to imiquimod.
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Cryotherapy has been used as monotherapy and in conjunction with other forms of treatment for excessive scars.
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Surgical procedures on the skin of the nose have to respect these different qualities and the nasal topography, including the nasal aesthetic subunits, to achieve the best possible result.
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While there have been a number of trials of topical 5-FU in the prevention of progression of lower genital tract neoplasia to invasive carcinoma in HIV-positive and HIV-negative women, mucosal use of topical 5-FU remains off-label.
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The primary outcome was a reduction of more than 25% in lesion size at 20 weeks.
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Diclofenac Sodium Gel should be used with caution in patients with active gastrointestinal ulceration or bleeding and severe renal or hepatic impairments.
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They represent clinical evidence that patients have sustained sufficient UV damage to the epidermis to cause visually abnormal skin changes and alteration in the DNA structure.
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Sexually Transmitted Diseases 2008; 35( 4): 346- 51.
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The quantitative composition of the vehicle cream used in the dermal mouse carcinogenicity study is the same as the vehicle cream used for imiquimod cream, minus the active moiety (imiquimod).
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Davis G, Wentworth J, Richard J (2000) Self-administered topical imiquimod treatment of vulvar intraepithelial neoplasia.
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Of 8 patients with objective responses who started treatment 1 year or more before data analysis, 5 had a response that lasted 1 year or more.
In addition, this gradual fibroplasia will ensure the injected area has the same texture as the adjacent tissue and that the product is not palpable.
Subjects applied up to two packets of ZYCLARA Cream or vehicle daily to the skin of the affected area (either entire face or balding scalp) for two 2-week treatment cycles separated by a 2-week no treatment period.
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Female patients should take special care if applying the cream at the opening of the vagina because local skin reactions on the delicate moist surfaces can cause pain or swelling, and may cause problems passing urine.
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The trough concentrations on Days 7 and 14 are obtained during outpatient treatment while the trough concentrations on Days 21 and 22 are obtained while the subjects are dosed in the clinical research facility.
The trial was an open label trial and the authors mentioned during the trial "A potential bias might result from lack of blinding patients and clinicians as to the treatment assignment".